Blood test for weight loss: your GLP-1 baseline
Your starting point before the first injection: blood sugar, cholesterol, pancreas, liver, kidneys, thyroid and nutrients in one measurement.
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Included Markers
21 markersInsulin (Fasting), ALT (Alanine Aminotransferase), TSH (Thyroid Stimulating Hormone), AST (Aspartate Aminotransferase), HDL Cholesterol, HbA1c (Glycated Hemoglobin), Bilirubin (Total), ApoB (Apolipoprotein B), Vitamin B12, Ferritin, Potassium, Sodium, Glucose (Fasting), Total Cholesterol, Albumin, Lipase, Creatinine, Vitamin D (25-OH), Triglycerides, Bilirubin (Direct), Bilirubin (Indirect)
Are you about to start a weight-loss injection such as Ozempic, Wegovy or Mounjaro, or are you already using semaglutide or tirzepatide? This blood test for weight loss is designed as your baseline: a starting point that lets you see what changes later on.
This GLP-1 baseline panel looks at a number of values across your blood sugar, cholesterol, liver, kidneys, thyroid and nutrients in a single blood draw. You order online, need no referral, and receive your results within a few working days with an assessment by a BIG-registered doctor.
Why this test?
Losing weight with GLP-1 medication changes a lot in your body at once: you eat less, your weight goes down and your metabolism adjusts. A baseline beforehand records how your values look now, so a later check has something to compare against.
Without a starting point, a result is harder to place. With a baseline blood test as your reference, you and a doctor can more easily see which values move along with your journey.
Who is this test for?
- People who are about to start a weight-loss injection and want to record a starting point
- People who have just begun semaglutide or tirzepatide and want to know their baseline values
- People who want their blood sugar, cholesterol, liver, kidneys and vitamins measured in one go
- People who want to arrange this without a referral
This blood test does not determine whether a weight-loss injection is suitable for you. That assessment always belongs with a doctor.
What is tested?
- Blood sugar and insulin: HbA1c, fasting glucose and fasting insulin.
- Cholesterol and fats: total cholesterol, HDL, triglycerides and ApoB.
- Liver: ALT, AST, bilirubin and albumin.
- Kidneys and minerals: creatinine, sodium and potassium.
- Thyroid: TSH.
- Pancreas: lipase.
- Nutrients: vitamin D, vitamin B12 and ferritin.
What can this test tell you?
Your blood sugar and insulin values can offer insight into your metabolism before you start. Your cholesterol and triglyceride values can provide context around your heart and vascular health, and your liver and kidney values give a view of how those organs are doing at that moment.
Because a weight-loss injection can strongly reduce appetite, nutrients such as vitamin D, vitamin B12 and ferritin may be relevant to know as a starting value. Together these are a snapshot, not a diagnosis, that you can discuss with a doctor.
How is the sample collected?
Blood is drawn at a certified collection point. In the Netherlands there are 700+ locations, which you choose yourself after ordering.
This is a blood test without a GP: you pick a location and a moment that suits you. The draw usually takes only a few minutes.
When is this test useful?
This baseline can be useful just before you begin a weight-loss injection, or in the first weeks after starting. That way you record your starting values at a moment when little has changed yet.
If you want to keep following your values over time, a later check fits well with this. Some people choose to test periodically to stay informed.
What do the results mean?
Your results appear with a reference range for each marker. Values outside that range are worth discussing with a doctor, who can place them in the context of your lifestyle, diet and weight-loss journey.
A single value outside the range does not immediately point to a problem. It is about the overall picture, and often about the change compared with your baseline.
What happens after the results?
Your results are usually in your personal dashboard within a few working days, with the measured values next to the reference ranges. You view them whenever it suits you.
Every blood test result includes a professional assessment from a BIG-registered doctor. For treatment decisions, discuss your results with your GP.
Frequently Asked Questions
From order to report in 4 steps
No waiting, no referral. Just order and go.
Choose your test
Choose your baseline test or follow-up, or build a custom test.
Receive your lab referral
You'll receive an email from ZorgDomein with a barcode within 1 business day. Orders placed outside office hours are processed from the next business day.
Get tested at a lab near you
Show the barcode on your phone and bring a valid ID. Done in under 15 minutes.
Receive your report from the doctor
A BIG-registered physician reviews your results and writes a personal report. On your dashboard within a few business days.
Choose your test
Choose your baseline test or follow-up, or build a custom test.
Receive your lab referral
You'll receive an email from ZorgDomein with a barcode within 1 business day. Orders placed outside office hours are processed from the next business day.
Get tested at a lab near you
Show the barcode on your phone and bring a valid ID. Done in under 15 minutes.
Receive your report from the doctor
A BIG-registered physician reviews your results and writes a personal report. On your dashboard within a few business days.
Always a location near you
With 700+ certified phlebotomy points across the Netherlands.
What We Test
This test includes 21 biomarkers for a clear picture of your health.
| No. | Biomarker | Unit | Turnaround |
|---|---|---|---|
| 01 | Insulin (Fasting) Fasting insulin measures the amount of insulin in your blood after an overnight fast. It helps assess how efficiently your body manages blood sugar and can reveal insulin resistance before glucose levels become abnormal. | pmol/L | 5 days |
| 02 | ALT (Alanine Aminotransferase) Your ALT value shows how much alanine aminotransferase is in your blood. This enzyme sits mainly in the liver. That makes ALT the most liver-specific of the routine enzymes. When it reaches the blood, liver cells have been damaged. In adult men the reference range runs to 45 u/l, and in women to 34 u/l. A mildly raised result is common and has several causes. Fatty liver leads that list, well ahead of alcohol and hepatitis. | u/l | 1 day |
| 03 | TSH (Thyroid Stimulating Hormone) TSH is thyroid-stimulating hormone. The pituitary gland makes it, and uses it to drive your thyroid. At the laboratory that runs the test the usual adult range runs from 0.27 to 4.20 mE/L. A high TSH usually fits an underactive thyroid. A low value usually fits an overactive one. That direction feels inverted, and it is. TSH is the pituitary signal, not the thyroid hormone itself. Laboratories use slightly different limits from one another. Always read the reference value printed on your own result. And a single measurement is never a diagnosis. | mu/l | 2 days |
| 04 | AST (Aspartate Aminotransferase) Your AST value shows how much aspartate aminotransferase is circulating in your blood. It is an enzyme that leaks out whenever cells are damaged. AST sits in the liver, but equally in skeletal muscle, heart muscle, kidneys, brain and red blood cells. That is why a raised AST is not, on its own, a liver value. A hard training session the day before explains the result more often than liver disease does. The reference range runs up to 35 u/l in men and 31 u/l in women. What the number means only becomes clear alongside ALT, gamma-GT and CK. | u/l | 1 day |
| 05 | HDL Cholesterol HDL cholesterol is the amount of cholesterol carried inside the HDL particles in your blood. Those particles pick cholesterol up from your tissues and from the artery wall and take it back to the liver. That transport is what earned HDL the nickname good cholesterol. The nickname is misleading. HDL is above all a mirror of your metabolism: the value drops with excess weight, insulin resistance, smoking and inactivity, and it is those factors that carry the risk. Drugs that raise HDL substantially do not reduce the number of cardiovascular events. And more is not always better: at very high values, mortality in large population studies turns back upwards. So never read your HDL on its own. It only takes on meaning alongside your triglycerides, your LDL and your overall risk profile. | mmol/l | 1 day |
| 06 | HbA1c (Glycated Hemoglobin) HbA1c (glycated haemoglobin) reflects your average blood sugar levels over the past 2-3 months. It is the gold standard for long-term blood sugar monitoring and diabetes management. | mmol/mol | 2 days |
| 07 | Bilirubin (Total) Total bilirubin measures the combined amount of direct and indirect bilirubin in your blood. Bilirubin is a waste product formed during the normal breakdown of red blood cells, and elevated levels may indicate liver disease, bile duct problems, or increased red blood cell destruction. | umol/l | 4 days |
| 08 | ApoB (Apolipoprotein B) Apolipoprotein B (ApoB) is the main protein on LDL and other atherogenic lipoproteins. Each atherogenic particle carries exactly one ApoB molecule, making it a precise measure of the total number of particles that can contribute to plaque formation. | g/l | 4 days |
| 09 | Vitamin B12 Vitamin B12 is considered essential for red blood cell formation, neurological function, and DNA synthesis. Deficiency may develop gradually and is sometimes associated with dietary patterns. Healthcare providers can help interpret your results. | pmol/l | 3 days |
| 10 | Ferritin Ferritin is a protein that stores iron, so your ferritin level shows how large your iron reserve is. Serum iron only measures how much iron is circulating in your blood at that moment; ferritin describes the reserve behind it. That reserve empties before your haemoglobin falls, so a low ferritin can already cause symptoms while your blood count still looks normal. Ferritin also rises with inflammation, infection and liver strain, which is why it can only be read properly alongside a CRP. Commonly used reference values are 30 to 400 µg/l for men and 15 to 150 µg/l for women, but your own laboratory report is what counts. | ug/l | 2 days |
| 11 | Potassium Potassium is an essential electrolyte and mineral that helps regulate heartbeat, muscle contractions, nerve signals, and fluid balance. It is one of the most important minerals for cardiovascular health. | mmol/l | 2 days |
| 12 | Sodium Sodium is a vital electrolyte that regulates fluid balance, blood pressure, and nerve and muscle function. It is the primary cation in extracellular fluid and is closely regulated by the kidneys. | mmol/l | 2 days |
| 13 | Glucose (Fasting) Fasting glucose measures the level of sugar (glucose) in your blood after an overnight fast. It is one of the primary tests used to screen for and monitor diabetes and pre-diabetes. | mmol/l | 1 day |
| 14 | Total Cholesterol Total cholesterol measures the combined amount of HDL, LDL, and VLDL cholesterol in your blood. It provides an overview of your lipid status but should be interpreted alongside individual components for a complete cardiovascular risk picture. | mmol/l | 1 day |
| 15 | Albumin Albumin is the most abundant protein in the blood, produced by the liver. It maintains fluid balance, transports hormones and nutrients, and serves as an indicator of liver and kidney function. | g/l | 2 days |
| 16 | Lipase Lipase is a pancreatic enzyme responsible for breaking down fats during digestion. It is more specific to the pancreas than amylase and is a key marker for diagnosing and monitoring pancreatic conditions such as pancreatitis. | u/l | 6 days |
| 17 | Creatinine Creatinine is a waste product that is continuously produced in your muscles. The kidneys filter it out of the blood and remove it in urine. The blood creatinine level is therefore a core number for kidney function. In Dutch it is written both as creatinine and as kreatinine. Because production depends on your muscle mass, the same figure reads differently per person. A raised creatinine does not automatically point to a kidney problem. This page explains what high and low values can mean. It also covers the everyday things that shift the result temporarily. | umol/l | 1 day |
| 18 | Vitamin D (25-OH) <p>Vitamin D is a fat-soluble vitamin. Its main job is the absorption of calcium and phosphate from the gut. That makes it decisive for bone metabolism.</p><p>The skin produces it under the influence of sunlight. Food and supplements supply a smaller share.</p> | nmol/l | 3 days |
| 19 | Triglycerides Triglycerides are the most common type of fat in the body, used for energy storage. Elevated levels may be associated with increased risk of cardiovascular disease, especially when combined with other lipid abnormalities. | mmol/l | 1 day |
| 20 | Bilirubin (Direct) Direct (conjugated) bilirubin is the water-soluble form of bilirubin that has been processed by the liver. Elevated levels may indicate bile duct obstruction or liver disease and are an important component of liver function assessment. | umol/l | 2 days |
| 21 | Bilirubin (Indirect) Indirect bilirubin is the part of your bilirubin that your liver has not yet processed. The value is not measured separately but calculated: your total bilirubin minus your direct bilirubin, in the same unit. That split helps to show where an abnormal total is coming from. This page explains what your indirect bilirubin result can mean. | umol/l | — |
| Your result arrives once the slowest test is finished: 6 days. This is indicative; turnaround varies per laboratory. | |||
Preparation
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Been ill? Wait a little
RequiredHad a fever, an infection or a vaccination in the past 2 weeks? Wait with the draw until you are fully recovered. These values react to inflammation and would give a distorted picture.
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Pause biotin
RequiredDo you take a supplement with biotin (vitamin B8, common in hair, skin and nail supplements)? Stop it 72 hours before the draw. Biotin interferes with the measurement of these values.
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No hard training beforehand
RequiredNo heavy training, long endurance sessions or anything that leaves you out of breath in the 48 hours before the draw. Normal walking is fine.
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No alcohol beforehand
RequiredDrink no alcohol in the 24 hours before the draw.
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Come fasting
RequiredFrom 22:00 the evening before, eat and drink nothing except water. That is at least 8 hours. Skip coffee, tea, chewing gum and smoking that morning. Plan the draw before 10:00.
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Timing worth knowing
Good to knowIf you repeat this test, pick the same time of day each time so the results compare.
- Water is always fine. Drink as usual beforehand, it makes the draw easier.
- Take your usual medication, unless your own doctor told you otherwise.
Extend this panel
Tests from the same field, run on the same sample. Same draw, no second appointment.
Related Measurements
Discover more measurements for a complete picture of your journey.
Insulin Resistance (HOMA-IR)
Insulin resistance becomes more relevant with age. Track it with fasting glucose, insulin and your HOMA-IR score.
GLP-1 Check-in Panel
The 3-month safety and progress check clinics do: pancreas, liver, kidneys, salts and your metabolic progress on GLP-1 medication.
GLP-1 Extended Panel
The 6-month measurement: everything from the check-in plus insulin, ApoB and your nutrients — especially relevant if you have been eating much less for a while.
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