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MCH and diet: iron, vitamin B12 and folate from food

According to Thuisarts, the body builds haemoglobin, the oxygen-carrying protein in the red blood cells, with iron, vitamin B12 and folate. How much haemoglobin is in the red blood cells is shown by the MCH value, which according to the NVKC is calculated from the haemoglobin and the number of red blood cells.

In anaemia, the MCH value can go two ways: according to the NVKC too low with iron deficiency and too high with a lack of vitamin B12 and/or folate. Where the MCH value lies can only be seen with a blood test.

For adults older than 18, the MCH reference value at Certe lies between 1700 and 2100 amol.

Doctor's Assessment Included

MCH is the average amount of haemoglobin, the protein that carries oxygen, in one red blood cell; it is calculated from haemoglobin and the red cell count. Certe uses 1700 to 2100 attomol for adults, equal to 1.70 to 2.10 femtomol.

  • A low MCH can fit iron deficiency or thalassaemia, a defect of the haemoglobin protein; a high MCH a lack of vitamin B12 or folate.
  • Star-SHL, Unilabs and Diagnostiek voor U publish no limit for MCH.

Reference Ranges

See the value that applies to you:

Choose male or female — this range differs by sex.

Enter your age — this range changes with age.

This range also depends on context such as cycle phase or sample material; the highlighted rows apply to your group.

Male Your group
fmol
Low 1.65 Normal 2.1 High
Female Your group
fmol
Low 1.65 Normal 2.1 High

Reference ranges may vary between laboratories. When you order a test, a BIG-registered doctor assesses your personal results in context. For treatment decisions, discuss your results with your GP.

Check your own value

MCH (Mean Corpuscular Hemoglobin): what Dutch laboratories use

Reference ranges by group, in amol
Certe · Male · 18 years and older 1700–2100 amol
1700 2100
Certe · Female · 18 years and older 1700–2100 amol
1700 2100
1600 2200 amol

Source: Certe

Each value as the laboratory itself publishes it, retrieved in 2026.

MCH (Mean Corpuscular Hemoglobin): what this test measures

According to the NVKC, the MCH test determines how much haemoglobin is in the red blood cells, and Certe gives the result in attomole (amol).

MCH (Mean Corpuscular Hemoglobin): why this value matters

The MCH value, according to the NVKC, is an aid in looking for the cause of anaemia, and according to Thuisarts that cause matters for the advice and the treatment.

MCH (Mean Corpuscular Hemoglobin): how the blood test works

Referral
No GP referral needed. After the order we arrange the referral through ZorgDomein, within one business day; orders after 17:00 or at the weekend start on the next business day. ZorgDomein emails a barcode, and that barcode is what the draw site needs.
The draw
A blood draw from a vein in the arm, at a partner laboratory's draw site. No home kit, no finger prick.
Where
650+ draw sites run by independent laboratories across the Netherlands. Draw sites

MCH (Mean Corpuscular Hemoglobin): when is testing worthwhile?

With a tired and weak feeling, dizziness or less colour in the face, symptoms that according to Thuisarts fit anaemia, a doctor can request an MCH test according to the NVKC to find the cause of anaemia.

MCH (Mean Corpuscular Hemoglobin): symptoms of a high or low value

Low Levels

According to the NVKC, iron deficiency can give anaemia with a low MCH. According to Thuisarts, too little iron can come from eating very little food with iron in it for years, or from a disease that makes it harder for iron to get into the body through the gut.

High Levels

According to the NVKC, too little vitamin B12 and/or folate can give anaemia with a high MCH. According to Thuisarts, food can contain too little vitamin B12 when someone eats very little, and the diabetes medicine metformin can cause too little vitamin B12. According to Thuisarts, folate is found in spinach, wholemeal bread and beans, among other foods.

MCH (Mean Corpuscular Hemoglobin): causes of a low or high value

What lowers the value

  • Iron deficiency

    A low MCH can point to anaemia from iron deficiency.

  • Thalassaemia

    In thalassaemia, a defect of the haemoglobin protein in the red blood cells, MCH is too low.

What raises the value

  • Vitamin B12 or folate deficiency

    A high MCH can point to anaemia from a lack of vitamin B12 or folate.

  • Fat or burst cells in the blood sample

    A lot of fat in the blood sample gives a falsely high MCH, and red blood cells that burst in the tube can do the same.

MCH (Mean Corpuscular Hemoglobin): lifestyle and this value

An abnormal MCH value goes to the GP. With too little folate, Thuisarts advises a daily pill of 0.5 milligrams of folate, and with too little vitamin B12 a daily pill of 1000 micrograms of vitamin B12.

MCH (Mean Corpuscular Hemoglobin): frequently asked questions

Can a vegan diet affect MCH?

According to Thuisarts, a vegan diet can give too little vitamin B12, and according to the NVKC a lack of vitamin B12 can go together with anaemia and a high MCH.

Can diabetes disturb the MCH result?

Yes, according to Gulati and colleagues (Annals of Laboratory Medicine, 2022), lipaemia, a lot of fat in the blood, is not uncommon in blood samples from people with diabetes, and according to the same article that fat in the sample makes the MCH falsely high.

MCH (Mean Corpuscular Hemoglobin): sources

  1. Certe, Bepalingenwijzer (referentiewaarden per bepaling), bepalingenwijzer.certe.nl, geraadpleegd 2026-10-01 (retrieved 2026) bepalingenwijzer.certe.nl
  2. NVKC, Alles over testen: MCH, allesovertesten.nl, geraadpleegd 2026-10-06 (retrieved 2026) allesovertesten.nl
  3. Gulati G, Uppal G, Gong J. Unreliable Automated Complete Blood Count Results: Causes, Recognition, and Resolution. Ann Lab Med 2022;42(5):515-530. (retrieved 2026) pmc.ncbi.nlm.nih.gov

Tests with related values

These panels measure values from the same category as this marker.

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