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Leukocytes and excess weight: what your white blood cell count says

Leukocytes, your white blood cells, come from your bone marrow and protect your body against infection by attacking bacteria, fungi and viruses.

The NVKC names infection, leukaemia, an injury and stress as causes of a high count, and chemotherapy, radiation and disorders of your immune system as causes of a low count. You only measure how many leukocytes you have with a blood test.

Leukocytes are counted in billions per litre (× 10^9/l); Star-SHL keeps 4.3 to 10.0 from age 18, Certe 4.0 to 10.0 from age 18, and Unilabs and Diagnostiek voor U 4.0 to 10.0 above age 15. According to a 2015 US review, excess weight is one of the non-malignant causes of a raised leukocyte count.

Doctor's Assessment Included

Leukocytes are the white blood cells that protect the body against infection. Star-SHL uses 4.3 to 10.0 × 10^9/l from age 18, Certe 4.0 to 10.0 from age 18, and Unilabs and Diagnostiek voor U 4.0 to 10.0 above age 15.

  • A raised leukocyte count is called leukocytosis, a lowered count leukopenia.
  • According to the NVKC, the leukocyte count is often part of a complete blood count.
  • A leukocyte count above 100,000 per cubic millimetre (mm³) is almost always caused by leukaemia or a related bone marrow disease, according to a 2015 US review.

Reference Ranges

See the value that applies to you:

Choose male or female — this range differs by sex.

Enter your age — this range changes with age.

This range also depends on context such as cycle phase or sample material; the highlighted rows apply to your group.

Male Your group
10^9/l
Low 4 Normal 10 High
Female Your group
10^9/l
Low 4 Normal 10 High

Reference ranges may vary between laboratories. When you order a test, a BIG-registered doctor assesses your personal results in context. For treatment decisions, discuss your results with your GP.

Check your own value

Leukocytes (WBC): what Dutch laboratories use

Reference ranges by group, in 10^9/l
Star-shl · Everyone · 18–110 years 4.3–10.0 10^9/l
4.3 10
Unilabs · Everyone · 15 years and older 4–10 10^9/l
4 10
Certe · Male · 18 years and older 4–10 10*9/L
4 10
Certe · Female · 18 years and older 4–10 10*9/L
4 10
Diagnostiek voor U · Everyone · 16 years and older 4–10 /nL
4 10
0 11 10^9/l

Source: Star-shl

Source: Unilabs

Source: Certe

Source: Diagnostiek voor U

Each value as the laboratory itself publishes it, retrieved in 2026.

Leukocytes (WBC): what this test measures

A leukocyte count counts your white blood cells per litre of blood, in billions (× 10^9/l). Neutrophils are one kind of white blood cell, and a shortage of neutrophils is called neutropenia.

Leukocytes (WBC): why this value matters

According to the NVKC, your leukocytes show whether your immune system is in order. A 2015 US review names excess weight together with smoking, some medicines, the absence of the spleen and chronic inflammatory diseases as non-malignant causes of a raised count.

Leukocytes (WBC): how the blood test works

Referral
No GP referral needed. After the order we arrange the referral through ZorgDomein, within one business day; orders after 17:00 or at the weekend start on the next business day. ZorgDomein emails a barcode, and that barcode is what the draw site needs.
The draw
A blood draw from a vein in the arm, at a partner laboratory's draw site. No home kit, no finger prick.
Where
650+ draw sites run by independent laboratories across the Netherlands. Draw sites

Leukocytes (WBC): when is testing worthwhile?

According to the NVKC, your leukocytes are often counted within a complete blood count, to detect inflammation or leukaemia or to see whether your immune system works well.

Leukocytes (WBC): symptoms of a high or low value

Low Levels

A low leukocyte count is called leukopenia; a shortage of neutrophils, one kind of white blood cell, is called neutropenia and begins below 1,500 per microlitre (µL) in adults and children older than 1 year, according to a 2025 US review. Among the acquired causes, that review names infections, medicines and a shortage of vitamin B12, folate or copper.

According to that review, the picture with a shortage of neutrophils ranges from no symptoms to a serious illness that needs admission.

High Levels

A raised leukocyte count can go with excess weight, but a 2015 US review names fatigue, night sweats, weight loss, easy bruising and bleeding as signs that might suggest a malignant cause. With such symptoms you have your count assessed by a doctor.

Leukocytes (WBC): causes of a low or high value

What lowers the value

  • Chemotherapy

    Chemotherapy suppresses the immune system and can lower the white cell count.

  • Radiation

    The white cell count can fall after radiation.

  • Immune system disorders

    A low white cell count points to an immune system that works less well, as in serious infectious diseases such as HIV.

What raises the value

  • Infection

    White blood cells attack bacteria, fungi and viruses, and during an infection their number is often raised.

  • Leukaemia

    In leukaemia white blood cells are produced without restraint.

  • Injury

    The white cell count can rise after an injury.

  • Stress

    Stress can also raise the white cell count.

Leukocytes (WBC): lifestyle and this value

A 2025 US review writes that acquired neutropenia, a shortage of neutrophils (one kind of leukocyte) that is not inherited, is treated by addressing the underlying cause. That review calls neutropenia with fever, at fewer than 500 neutrophils per microlitre (µL), an emergency in cancer care that needs urgent assessment.

Leukocytes (WBC): frequently asked questions

Can excess weight raise my leukocytes?

Yes, excess weight can raise the leukocyte count: a 2015 US review counts it among the non-malignant causes of leukocytosis, a raised white blood cell count.

Which deficiencies can give a low neutrophil count?

A shortage of vitamin B12, folate or copper can give a low count of neutrophils, one kind of leukocyte, according to a 2025 US review.

Leukocytes (WBC): sources

  1. Star-shl, Labbepalingen (referentiewaarden per bepaling), star-shl.nl, geraadpleegd 2026-10-01 (retrieved 2026) star-shl.nl
  2. Unilabs, Bepalingenklapper (referentiewaarden per bepaling), bepalingenklapper.nl, geraadpleegd 2026-10-01 (retrieved 2026) bepalingenklapper.nl
  3. Certe, Bepalingenwijzer (referentiewaarden per bepaling), bepalingenwijzer.certe.nl, geraadpleegd 2026-10-01 (retrieved 2026) bepalingenwijzer.certe.nl
  4. Diagnostiek voor U, eLabgids (Referentiewaarden DvU), diagnostiek.getincontrol.eu, geraadpleegd 2026-10-01 (retrieved 2026) diagnostiek.getincontrol.eu
  5. NVKC, Alles over testen: WBC, allesovertesten.nl, geraadpleegd 2026-10-03 (retrieved 2026) allesovertesten.nl

Tests with related values

These panels measure values from the same category as this marker.

Medical reviewer

Medical standards

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Medical policy
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Leukocytes (WBC)

€9,-