Health Assessment Report
ExampleGLP-1 progress panel · 5 biomarkers
Patient details
- Name
- Lisa Hoekstra
- Gender
- Female
- Age
- 45 years
- Date of birth
- 08-02-1981
Test details
- Test Date
- 22-06-2026
- Report date
- 25-06-2026
- Location
- Groningen Centrum
- Laboratory
- Star-SHL
5
Total Markers
2
In Range
3
Needs Attention
Overall Assessment
This report compares your week 0 baseline with your week 12 check. Four of the five values have improved, and three of them moved from outside the range to inside it.
Your HbA1c fell from 44 to 38 mmol/mol, your fasting glucose from 6.4 to 5.3 mmol/L and your fasting insulin from 21.8 to 11.2 mU/L. That last one is the most important of the three: it means your body needs less insulin to hold a lower blood glucose.
Key Findings
HbA1c from 44 to 38 mmol/mol
GoodFrom above the 42 limit to comfortably below it. HbA1c reflects your average blood glucose over the past two to three months, so this fall covers almost exactly the period of your programme.
Fasting insulin halved (21.8 to 11.2 mU/L)
GoodThe most meaningful change in this report. A lower insulin alongside a lower glucose means your insulin sensitivity has improved — your body is doing more with less.
ALT normalised (38 to 26 U/L)
GoodYour liver value moved from just above the limit to well within range. Fat content in the liver usually falls with weight loss, and that is generally what you are seeing here.
Lipase stable (42 to 45 U/L) — safety check
InformationalThis value is not supposed to improve. Lipase is measured because GLP-1 medication can, rarely, cause pancreatitis. Stable and within range is exactly the desired outcome.
Detailed Analysis
Metabolic
GoodAll three metabolic values have improved.
Your HbA1c went from 44 to 38 mmol/mol. The limit is 42, so you moved from above it to below it. HbA1c measures what proportion of your hemoglobin has been glycated, which makes it lag reality — today's value describes the past two to three months.
Your fasting glucose fell from 6.4 to 5.3 mmol/L, also from above the range into it.
The most important change is your fasting insulin: from 21.8 to 11.2 mU/L. Both values fall formally within the reference range, so neither was ever flagged as abnormal. But the fall itself is what counts. A high insulin alongside a high glucose means your body is working hard to keep blood sugar in check. Now less insulin is needed for a lower glucose, and that is what insulin sensitivity means.
Liver
GoodYour ALT fell from 38 to 26 U/L, from just above the 34 upper limit to comfortably below it. A mildly raised ALT in the context of excess weight is often linked to fat accumulation in the liver, which usually decreases with weight loss.
Your lipase went from 42 to 45 U/L, staying in the middle of the 13 to 60 range. This value is not in the panel to improve. Lipase is a pancreatic enzyme and is monitored during a GLP-1 programme because this medication can, rarely, cause pancreatitis. A stable value within range is the good news here.
Recommendations
Keep measuring lipase, even now it is fine
Precisely because this value is stable, it is useful: you now have two measurements as your own baseline. Keep including it at every check while you are on the medication, and contact your doctor about persistent abdominal pain that radiates to your back.
Next check in twelve weeks
HbA1c needs roughly that long to reflect a new change. Measuring sooner mostly shows noise.
Always test fasting and at the same time of day
Glucose and insulin are sensitive to when you last ate. Only measurements taken under the same conditions are comparable; otherwise you are comparing two different mornings instead of twelve weeks of progress.
Next Steps
There is no reason to change anything about your programme. Schedule the next measurement in twelve weeks, again fasting and at the same time of day.
Contact your doctor about persistent abdominal pain radiating to your back, or about any other symptoms you attribute to the medication. This report does not replace a consultation.
Your Test Results
Liver
4Your Trend
What It Measures
Lipase is an enzyme produced primarily by the pancreas that plays an essential role in fat digestion. It breaks down dietary triglycerides into fatty acids and glycerol, which the body can then absorb. This test measures the concentration of lipase in your blood. Under normal circumstances, only small amounts of lipase are present in the bloodstream. Significantly elevated levels are highly suggestive of pancreatic inflammation or damage, making lipase a more reliable indicator of pancreatitis than amylase.
Lifestyle Tips
Limiting alcohol consumption is essential, as alcohol is one of the leading causes of pancreatitis. A low-fat diet can reduce the workload on the pancreas and may help prevent flare-ups in individuals with pancreatic conditions. Eat smaller, more frequent meals to support digestion. Avoid smoking, which is an independent risk factor for pancreatic disease. Stay well hydrated and maintain a healthy weight, as obesity increases the risk of gallstones, which can cause pancreatitis.
Your Trend
What It Measures
The test measures how much ALT is circulating in your blood. The result is given in units per litre, abbreviated u/l. ALT stands for alanine aminotransferase.<br><br>Older reports sometimes carry the former name SGPT. It is the same enzyme and the same measurement.<br><br>The enzyme works inside the cell. It moves an amino group between two compounds. Your body needs that step to convert amino acids into fuel.<br><br>As long as a cell is intact, the enzyme stays inside it. Only when liver cells are damaged does ALT leak out.<br><br>Where ALT sits determines what the result is worth. The enzyme is concentrated mainly in the liver, far more than anywhere else. Small amounts sit in kidney, heart and skeletal muscle. That distribution makes ALT more liver-specific than AST, which occurs in many tissues at once.<br><br>This is why ALT rarely appears alone on a report. You usually see it beside AST, gamma-GT, alkaline phosphatase and bilirubin. Each enzyme points in a different direction.<br><br>ALT and AST come from the liver cell itself. Gamma-GT and alkaline phosphatase come from the bile ducts. That split guides the further investigation a doctor chooses.<br><br>The measurement itself says nothing about the cause. It only adds up how much enzyme is circulating. What a high ALT value means becomes clear only alongside the other liver values.
When Levels Are High
Raised values usually cause no symptoms. That is precisely why this enzyme is measured. The liver rarely reports damage with pain, certainly not at an early stage. When symptoms are present, they are not very specific. Fatigue, reduced appetite and nausea are the most common. Some people notice a nagging feeling in the upper right abdomen. A smaller group of symptoms points more clearly at the liver. Yellowing of the skin or the whites of the eyes belongs there. Dark urine and unusually pale stools belong in the same list. Itching without a rash also occurs. That combination does not belong in an online explanation but with a doctor, and urgently. The same applies to a strongly raised result with fever or confusion. The size of the rise drives the urgency. Up to roughly three times the upper limit is usually a matter of repeating and looking further. Above ten times the upper limit, this is an acute picture.
Lifestyle Tips
The biggest gain usually sits with weight, not with a supplement. Fatty liver is the most common reason for a mildly raised result in the Netherlands. Gradual weight loss combined with regular exercise is the best-supported approach.<br><br>A fall of roughly seven percent of body weight usually brings liver values down clearly. Do not expect an effect within a week.<br><br>Alcohol is the second dial you can turn. Heavy alcohol use burdens the liver directly. A period without alcohol often shows, on a repeat measurement, how much of the result was attributable to drink.<br><br>Sugar and fast carbohydrates deserve separate attention. Fructose from soft drinks and juices contributes to fat accumulation in the liver. That is a structural route, not a day-to-day one.<br><br>Go through your medicines and supplements with your GP or pharmacist. Include over-the-counter products and herbal preparations. Never stop a prescribed medicine on your own initiative because of a blood result. Discuss it first.<br><br>Finally, schedule the draw sensibly. Leave 48 to 72 hours after a heavy or unaccustomed training session.
Your Trend
What It Measures
Lipase is an enzyme produced primarily by the pancreas that plays an essential role in fat digestion. It breaks down dietary triglycerides into fatty acids and glycerol, which the body can then absorb. This test measures the concentration of lipase in your blood. Under normal circumstances, only small amounts of lipase are present in the bloodstream. Significantly elevated levels are highly suggestive of pancreatic inflammation or damage, making lipase a more reliable indicator of pancreatitis than amylase.
Lifestyle Tips
Limiting alcohol consumption is essential, as alcohol is one of the leading causes of pancreatitis. A low-fat diet can reduce the workload on the pancreas and may help prevent flare-ups in individuals with pancreatic conditions. Eat smaller, more frequent meals to support digestion. Avoid smoking, which is an independent risk factor for pancreatic disease. Stay well hydrated and maintain a healthy weight, as obesity increases the risk of gallstones, which can cause pancreatitis.
Your Trend
What It Measures
The test measures how much ALT is circulating in your blood. The result is given in units per litre, abbreviated u/l. ALT stands for alanine aminotransferase.<br><br>Older reports sometimes carry the former name SGPT. It is the same enzyme and the same measurement.<br><br>The enzyme works inside the cell. It moves an amino group between two compounds. Your body needs that step to convert amino acids into fuel.<br><br>As long as a cell is intact, the enzyme stays inside it. Only when liver cells are damaged does ALT leak out.<br><br>Where ALT sits determines what the result is worth. The enzyme is concentrated mainly in the liver, far more than anywhere else. Small amounts sit in kidney, heart and skeletal muscle. That distribution makes ALT more liver-specific than AST, which occurs in many tissues at once.<br><br>This is why ALT rarely appears alone on a report. You usually see it beside AST, gamma-GT, alkaline phosphatase and bilirubin. Each enzyme points in a different direction.<br><br>ALT and AST come from the liver cell itself. Gamma-GT and alkaline phosphatase come from the bile ducts. That split guides the further investigation a doctor chooses.<br><br>The measurement itself says nothing about the cause. It only adds up how much enzyme is circulating. What a high ALT value means becomes clear only alongside the other liver values.
Lifestyle Tips
The biggest gain usually sits with weight, not with a supplement. Fatty liver is the most common reason for a mildly raised result in the Netherlands. Gradual weight loss combined with regular exercise is the best-supported approach.<br><br>A fall of roughly seven percent of body weight usually brings liver values down clearly. Do not expect an effect within a week.<br><br>Alcohol is the second dial you can turn. Heavy alcohol use burdens the liver directly. A period without alcohol often shows, on a repeat measurement, how much of the result was attributable to drink.<br><br>Sugar and fast carbohydrates deserve separate attention. Fructose from soft drinks and juices contributes to fat accumulation in the liver. That is a structural route, not a day-to-day one.<br><br>Go through your medicines and supplements with your GP or pharmacist. Include over-the-counter products and herbal preparations. Never stop a prescribed medicine on your own initiative because of a blood result. Discuss it first.<br><br>Finally, schedule the draw sensibly. Leave 48 to 72 hours after a heavy or unaccustomed training session.
Metabolic
6Your Trend
What It Measures
This test measures the percentage of haemoglobin in red blood cells that has glucose attached to it. Higher percentages indicate higher average blood sugar over the preceding months.
When Levels Are High
Elevated HbA1c may not cause immediate symptoms but indicates poor long-term blood sugar control. Over time, this may be associated with increased risk of cardiovascular, nerve, kidney, and eye complications.
Lifestyle Tips
Consistent carbohydrate management, regular physical activity, maintaining a healthy weight, and managing stress are key to keeping HbA1c within a healthy range. Small, sustained changes are more effective than drastic diets.
Your Trend
What It Measures
This test measures blood glucose after fasting for at least 8 hours. It reflects your body's baseline ability to regulate blood sugar without the influence of recent food intake.
When Levels Are High
High fasting glucose may initially cause no symptoms but over time can lead to increased thirst, frequent urination, fatigue, blurred vision, and slow wound healing.
Lifestyle Tips
Maintain a balanced diet with controlled portions, regular physical activity, a healthy weight, and adequate sleep. Limit refined sugars and processed carbohydrates. These lifestyle factors play a key role in blood sugar management.
Your Trend
What It Measures
This test measures baseline insulin levels in a fasting state. Elevated fasting insulin often precedes elevated fasting glucose, making it an early indicator of metabolic dysfunction.
Lifestyle Tips
Regular exercise, especially resistance training and aerobic activity, can improve insulin sensitivity. Reduce refined carbohydrates, prioritise protein and fibre, and maintain a healthy weight.
Your Trend
What It Measures
This test measures the percentage of haemoglobin in red blood cells that has glucose attached to it. Higher percentages indicate higher average blood sugar over the preceding months.
Lifestyle Tips
Consistent carbohydrate management, regular physical activity, maintaining a healthy weight, and managing stress are key to keeping HbA1c within a healthy range. Small, sustained changes are more effective than drastic diets.
Your Trend
What It Measures
This test measures blood glucose after fasting for at least 8 hours. It reflects your body's baseline ability to regulate blood sugar without the influence of recent food intake.
Lifestyle Tips
Maintain a balanced diet with controlled portions, regular physical activity, a healthy weight, and adequate sleep. Limit refined sugars and processed carbohydrates. These lifestyle factors play a key role in blood sugar management.
Your Trend
What It Measures
This test measures baseline insulin levels in a fasting state. Elevated fasting insulin often precedes elevated fasting glucose, making it an early indicator of metabolic dysfunction.
Lifestyle Tips
Regular exercise, especially resistance training and aerobic activity, can improve insulin sensitivity. Reduce refined carbohydrates, prioritise protein and fibre, and maintain a healthy weight.
Assessed by a BIG-registered doctor
This report was prepared by a BIG-registered doctor. It does not replace a personal medical consultation. Always consult your general practitioner if you have questions.